Though the original "Ultra Instinct" Shaggy memes began to die down, they have recently resurged due to the Avengers: Endgame film. (Don't worry, this fun fact includes no spoilers.)
After the original meme lost popularity, a brand new Shaggy meme has now gone viral about the Infinity Stones actually being Shaggy's kidney stones. The memes also depict Shaggy beating up the movie's villain, Thanos, to get them back, thus ending the film without the Avengers having to do anything.
Here are some of the best:
Also, one more unrelated one just because it's amusing lol.